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In addition, esculin induces endoplasmic reticulum stress through the regulation of eukaryotic translation initiation factor 2/CHOP and Nrf2/HO-1 pathways via the PERK signaling pathway

Our model suggests that the large male-female differences in GSH concentration and the velocity of its synthesis cause females to be less sensitive to APAP toxicity compared to males

Inhibition of glutaminase selectively suppresses the growth of primary acute myeloid leukemia cells with IDH mutations

Strikingly, Gclc ablation increased mTORC1 activation in FoB to a level similar to that found in MZB

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